Sensitivity Analysis of the HIV-1 Infection Model with Saturated CTL Immune Response
DOI:
https://doi.org/10.17762/msea.v71i4.792Abstract
Recently, a large number of mathematical models that are described by delay differential equations (DDEs) have appeared in the life sciences. This is an article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such as dynamical diseases and cell growth dynamics. In this paper, we present a delay differential model to describe the HIV-1 dynamics model with a CTL immune response with two time delays. We performed a sensitivity analysis of the HIV-1 dynamics model that reveals the parameter values have a major impact on the model dynamics. Our goal is to determine which parameter has the greatest influence on model dynamics and can be verified using graphs.